Complementary and alternative medicine dialogue lacking between patients, providers

Despite their high use of complementary and alternative medicine (CAM), Americans over the age of 50 often do not discuss CAM use with their health care providers, a survey indicates. The results, from AARP and the National Center for Complementary and Alternative Medicine (NCCAM) at the National Institutes of Health were released today.

Researchers complete whole-exome sequencing of skin cancer

A team led by researchers at the National Institutes of Health is the first to systematically survey the landscape of the melanoma genome, the DNA code of the deadliest form of skin cancer. The researchers have made surprising new discoveries using whole-exome sequencing, an approach that decodes the 1-2 percent of the genome that contains … Read more

Scientists identify gene that could hold the key to muscle repair

Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly people who lose muscle strength following bed rest find it difficult or impossible to regain. Now, researchers at the National Institute of Arthritis and Musculoskeletal … Read more

Analysis of opioid prescription practices finds areas of concern

An analysis of national prescribing patterns shows that more than half of patients who received an opioid prescription in 2009 had filled another opioid prescription within the previous 30 days. This report also suggested potential opportunities for intervention aimed at reducing abuse of prescription opioids. Researchers from the National Institute on Drug Abuse (NIDA), a … Read more

USU study maps hotspots of genetic rearrangement

Researchers have zoomed in on mouse chromosomes to map hotspots of genetic recombination — sites where DNA breaks and reforms to shuffle genes. The findings of the scientists at the National Institutes of Health and Uniformed Services University of Health Sciences (USU) have the potential to improve the detection of genes linked to disease and … Read more

New warm line helps clinicians tackle patients’ substance abuse

A free, nationwide service was launched today to help primary care providers seeking to identify and advise substance-abusing patients. The service, Physician Clinical Support System for Primary Care (PCSS-P), offers peer-to-peer mentorship and resources on incorporating screening and follow-up into regular patient care. PCSS-P is a project of the National Institute on Drug Abuse (NIDA), … Read more

Bypass surgery, medications both options to be considered for heart failure patients with coronary artery disease

A new study found that coronary artery bypass surgery added to medical therapy for selected chronic heart failure patients offered benefits over medical therapy alone. The combination of the two treatment approaches reduced the combined rate of deaths and heart-related hospital stays by 15 percent, although the total number of deaths between the two groups … Read more

Distribution of cancers in the HIV/AIDS population is shifting

As treatments for HIV/AIDS improve and patients are living longer, the distribution of cancers in this population has undergone a dramatic shift in the United States. While cases of the types of cancer that have been associated with AIDS progression have decreased, cases of other types of cancer are on the rise. These results, reported … Read more

Researchers identify cause and new treatment for common recurrent fever in children

A preliminary study conducted by a team at the National Institutes of Health has identified a promising new treatment in children for the most common periodic fever disease in children. The syndrome is called periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis — or PFAPA — and is characterized by monthly flare-ups of … Read more

Cells’ energy factories linked to damaging inflammation

Scientists have discovered that molecules called reactive oxygen species (ROS) produced by the energy factories, or mitochondria, in cells, may play a role in a rare inherited disorder in which uncontrolled inflammation damages the body’s tissues. Their research in human and mouse cells suggests that blocking these molecules could reduce inflammation in TNF receptor-associated periodic … Read more