A novel technique that enables scientists to measure and document tumor-inducing changes in DNA is providing new insight into the earliest events involved in the formation of leukemias, lymphomas and sarcomas, and could potentially lead to the discovery of ways to stop those events.

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  1. Adverse Cardiovascular Events Reported in Testosterone Trial in Older Men A clinical trial of testosterone treatment in older men, reported June 30 online in the New England Journal of Medicine, has found a higher rate of adverse cardiovascular events, such as heart attacks and elevated blood pressure, in a group of older men receiving testosterone gel compared to those receiving placebo. Due to these events, […]...
  2. Scientists find approach to enhance and prolong immune attack against tumor cells Investigators have identified a new class of human immune cells that behave like stem cells. These cells, a subtype of T lymphocytes, which comprise a small fraction of white blood cells, may prove more effective than any previously reported type of T cell for treating tumors. The study, by scientists at the National Cancer Institute […]...
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  4. Researchers extend use of gene therapy to treat a soft tissue tumor Researchers extend use of gene therapy to treat a soft tissue tumor...
  5. Medicare Card, Scientists Identify Markers, Human Breast Cancer Cells, Linked to Development of an Aggressive, But Less Common Form of Breast Cancer Scientists have identified a group of surface markers on cells linked to an aggressive type of breast cancer called estrogen receptor-negative cancer. In this preliminary study, estrogen-negative breast cancer developed when three markers, CD44+, CD49fhi, and CD133hi were present simultaneously on the surface of human cells taken from breast cancer patients and transplanted into a […]...
  6. Study identifies gene that suppresses cell’s immune activation A new study of prostate tumors has shown that a gene, FOXO3, suppresses activation of cells related to immunity and thus leads to a reduced immune response against a growing cancer. One of the main problems in treating cancer by vaccine or immunotherapy is that tumors often evade the body’s immune response — and one […]...
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  8. Organisation of Economic Co-Operation and Development (OECD) Pathways to Transitions Projec The Social Security Administration (SSA) is currently providing funds to help support OECD’s five-year study on Pathways to Transitions for People with Disability into Tertiary Education and Work....
  9. Level of tumor protein indicates chances cancer will spread Researchers at the National Institutes of Health and the University of Hong Kong have discovered that high levels of a particular protein in cancer cells are a reliable indicator that a cancer will spread....
  10. Commissioned study identifies gaps in funding success rates for black researchers Black applicants from 2000-2006 were 10 percentage points less likely than white applicants to be awarded research project grants from the National Institutes of Health after controlling for factors that influence the likelihood of a grant award, according to an NIH-commissioned study in the journal Science. In an accompanying commentary, NIH Director Francis Collins, M.D., […]...
  11. NIDA Avant-Garde-Medications Development Award winners announced Scientists proposing to develop vaccines against methamphetamine and nicotine have been selected to receive NIDA’s second Avant-Garde Awards for Innovative Medication Development Research. The two scientists, Dr. Thomas Kosten, of Baylor College of Medicine, Houston, and Dr. Peter Burkhard, of the University of Connecticut, Storrs, will each receive $500,000 per year for five years to […]...
  12. In NIH-funded study, researchers uncover early step in the cascade of brain events leading up to addiction A regulatory protein best known for its role in a rare genetic brain disorder also may play a critical role in cocaine addiction, according to a recent study in rats, funded by the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health. The study was published today in the journal […]...
  13. Funded study proposes new method to predict fertility rates Researchers supported by the National Institutes of Health have developed a new statistical technique to forecast changes in fertility rates. The new method mathematically compensates for uncertainty and is expected to allow governments to plan more reliably for the infrastructure and social services needed to accommodate large-scale population changes....
  14. Medicare Card, Non-profits sign research and development agreement The National Institutes of Health today announced an agreement with two non-profit organizations to accelerate the development of potential clinical therapies for rare blood cancers....
  15. Blueprint empowers drug development for nervous system disorders The National Institutes of Health has made awards to investigators across the United States for an ambitious set of projects seeking to develop new drugs for disorders of the nervous system....