Researchers develop mouse with ‘off switch’ in key brain cell population

NIH-funded scientists have developed a strain of mice with a built-in off switch that can selectively shut down the animals’ serotonin-producing cells, which make up a brain network controlling breathing, temperature regulation, and mood. The switch controls only the serotonin-producing cells, and does not affect any other cells in the animal’s brains or bodies.

Research convenes national summit on The Science of Compassion: Future Directions in End-of-Life and Palliative Care

The National Institute of Nursing Research (NINR), a component of the National Institutes of Health, and its partners will host The Science of Compassion: Future Directions in End-of-Life and Palliative Care. This trans-NIH summit aims to examine the current status of end-of-life and palliative care research and practice; propose strategies to address current barriers to … Read more

Researchers identify gene variant in Proteus syndrome

A team of researchers has identified the genetic mutation that causes Proteus syndrome, a rare disorder in which tissue and bone grows massively out of proportion. The discovery, which has implications for potential drug therapies and even cancer, appears in the July 27, 2011, early online edition of the New England Journal of Medicine. The … Read more

Standard aplastic anemia therapy improves patient outcomes better than newer version

A comparison clinical study of two aplastic anemia treatments found that ATGAM, currently the only licensed aplastic anemia drug in the United States, improved blood cell counts and survival significantly more than Thymoglobulin, a similar but reportedly more potent treatment. The research was carried out by the National Heart, Lung and Blood Institute (NHLBI), part … Read more

Director of Intramural Center for Regenerative Medicine

National Institutes of Health Director Francis S. Collins, M.D., Ph.D., has announced the appointment of Mahendra S. Rao, M.D., Ph.D. as the director for the new NIH Intramural Center for Regenerative Medicine (NIH-CRM). The NIH-CRM is an initiative to create a world-class center of excellence in stem cell technology on the NIH campus, including induced … Read more