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1. Medicare Card, Gene hastens kidney disease progression in African-Americans A gene variant common in African-Americans predicts that people with that gene who also have chronic kidney disease (CKD) are twice as likely to progress to kidney failure as African-Americans without the high-risk gene and white people with CKD. People with the high-risk gene also tend to lose kidney function at twice the rate of […]...
2. Medicare Card, NIH researchers identify candidate drug to treat Batten disease Medicare Card, NIH researchers identify candidate drug to treat Batten disease...
3. Medicare, NIH researchers identify genetic elements influencing the risk of type 2 diabetes Medicare, NIH researchers identify genetic elements influencing the risk of type 2 diabetes: A team led by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, has captured the most comprehensive snapshot to date of DNA regions that regulate genes in human pancreatic islet cells, a subset of […]...
4. Medicare, NIH scientists identify possible gene target for treating a form of lymphoma Researchers have identified a mutation in a gene that could lead to targeted therapies for certain lymphoma patients whose cure rates are currently poor. Mutation of the MYD88 gene was found to be one of the most frequent genetic abnormalities in a form of cancer known as diffuse large B cell lymphoma. MYD88 encodes a […]...
5. Medicare Card, NIH supports new studies to find Alzheimer’s biomarkers in Down syndrome Medicare Card, NIH supports new studies to find Alzheimer’s biomarkers in Down syndrome...
6. Medicare Card, NIH scientists uncover genetic explanation for frustrating syndrome Medicare Card, NIH scientists uncover genetic explanation for frustrating syndrome...
7. Researchers Identify Gene Mutations Underlying Risk for Most Common Form of Parkinson’s Disease Parkinson's disease, which affects about 1.5 million Americans, is a progressive neurologic disorder caused by the degeneration of nerve cells in the portion of the brain that controls movement....
8. Scientists show how gene variant linked to ADHD could operate A study using mice provides insight into how a specific receptor subtype in the brain could play a role in increasing a person’s risk for attention-deficit hyperactivity disorder (ADHD). The research, conducted by the Intramural Research Program (IRP) at the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, could also […]...
9. Medicare, Gene Variant that may Prevent African Sleeping Sickness also Leads to Increased Chance of Kidney Disease National Institutes of Health researchers and grantees have found that gene variants in APOL1, more common in African Americans, come with both health risk and reward, as reported in the July 15 online issue of Science....
10. Medicare Card, NIH and collaborators identify the genomic cause for Carey-Fineman-Ziter syndrome Medicare Card, NIH and collaborators identify the genomic cause for Carey-Fineman-Ziter syndrome...
11. Medicare: Researchers identify key proteins of inner ear transduction channel National Institutes of Health-funded researchers have identified two proteins that may be the key components of the long-sought after mechanotransduction channel in the inner ear — the place where the mechanical stimulation of sound waves is transformed into electrical signals that the brain recognizes as sound....
12. Discovered gene causes Kabuki syndrome Using a new, rapid and less expensive DNA sequencing strategy, scientists have discovered genetic alterations that account for most cases of Kabuki syndrome, a rare disorder that causes multiple birth defects and mental retardation. Instead of sequencing the entire human genome, the new approach sequences just the exome, the 1-2 percent of the human genome […]...
13. Researchers restore children’s immune systems with refinements in gene therapy Researchers have demonstrated that a refined gene therapy approach safely restores the immune systems of some children with severe combined immunodeficiency (SCID). The rare condition blocks the normal development of a newborn’s immune system, leaving the child susceptible to every passing microbe. Children with SCID experience chronic infections, which usually triggers the diagnosis. Their lifespan […]...
14. Scientists identify gene that could hold the key to muscle repair Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly people who lose muscle strength following bed rest find it difficult or impossible to regain. Now, researchers at the National Institute of Arthritis and Musculoskeletal […]...
15. Common Fund researchers link genetic variants and gene regulation in many common diseases Researchers supported by the NIH Common Fund have discovered that genetic differences linked to a wide variety of diseases, including many adult-onset diseases, influence how genes are turned on, or activated, during fetal development. These findings may help to explain why some environmental exposures in utero or during early childhood are known to increase risk […]...