In a study in mice, researchers found that they could reduce the progression of the toxic aggregates of a protein known as a-synuclein that are found in the brains of Parkinson’s disease patients. The results suggest that another protein called lymphocyte-activation gene 3 (LAG3) plays a role in transmitting a-synuclein aggregates from one brain cell to another and could provide a possible target to slow the progression of Parkinson’s disease. The study, published in Science, was partially funded by the National Institutes of Health’s National Institute of Neurological Disorders and Stroke (NINDS).

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