Funds development of tissue chips to help predict drug safety

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1. NHGRI funds development of revolutionary DNA sequencing technologies Researchers today received more than $14 million in grants to develop DNA sequencing technologies that will rapidly sequence a person’s genome for $1000 or less. The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, awarded the grants to enable the everyday use of DNA sequencing technologies by biomedical researchers and ... Read more...
2. NIEHS Awards Recovery Act Funds Focus More Research on Health and Safety of Nanomaterials NIEHS Awards Recovery Act Funds to Focus More Research on Health and Safety of Nanomaterials ...
3. New model of ALS is based on human cells from autopsied tissue By isolating cells from patients’ spinal tissue within a few days after death, researchers funded by the National Institutes of Health have developed a new model of the paralyzing disease amyotrophic lateral sclerosis (ALS). They found that during the disease, cells called astrocytes become toxic to nerve cells — a result previously found in animal ... Read more...
4. Commonly used three-drug regimen for idiopathic pulmonary fibrosis found harmful The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has stopped one arm of a three arm multi-center, clinical trial studying treatments for the lung-scarring disease idiopathic pulmonary fibrosis (IPF) for safety concerns....
5. Medicare Help, Immune Cell’s Role, Lupus Nephritis Demonstrated, Paves Way for Safety Testing, of Potential New Use for Asthma Drug National Institutes of Health scientists have discovered that the activation of immune cells called basophils causes kidney damage in a mouse model of lupus nephritis. These findings and the team’s associated research in humans may lead to new treatments for this serious disease, a severe form of systemic lupus erythematosus (SLE) that affects the kidneys ... Read more...
6. Delayed stem cell therapy following heart attack is safe but not effective Stem cells obtained from bone marrow, known as BMCs, can be safely injected into people 2-3 weeks following a heart attack, reports a new clinical trial supported by the National, Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health. However, while safe, the BMCs did not improve heart function six months ... Read more...
7. Medicare – Lung Disease the Links to Health People with a mild form of a common lung condition—even those without symptoms—are at increased risk for heart problems, according to a new study. This is the first report that mild, often-symptomless chronic obstructive pulmonary disease (COPD) may be linked to the heart's pumping ability...
8. Therapeutics for Rare and Neglected Diseases Program announces next round of drug development projects Researchers will begin drug development projects for rare and neglected diseases that include potential treatments for a musculoskeletal disorder, a cognitive dysfunction disorder, a virus that affects the central nervous system of newborns, a parasitic worm infection, a form of muscular dystrophy and a rare lung disease....
9. Medicare Medical Care, Rapid Development of Drug-Resistant, 2009 H1N1 Influenza Reported in Two Cases Two people with compromised immune systems who became ill with 2009 H1N1 influenza developed drug-resistant strains of virus after less than two weeks on therapy, report doctors from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. Doctors who treat prolonged influenza infection should be aware that even a short course of antiviral treatment may lead to drug-resistant virus, say the authors, and clinicians should consider this possibility as they develop initial treatment strategies for their patients who have impaired immune function....
10. MedicareCard urges women to protect their heart health As part of American Heart Month, on Wednesday, Feb. 8, 2012, the National Heart, Lung, and Blood Institute’s (NHLBI’s) The Heart Truth campaign, with the support of the Foundation for the National Institutes of Health (FNIH), will showcase its signature event, the Red Dress Collection 2012 at Mercedes-Benz Fashion Week in New York City....
11. Medicare Card, Scientists Identify Markers, Human Breast Cancer Cells, Linked to Development of an Aggressive, But Less Common Form of Breast Cancer Scientists have identified a group of surface markers on cells linked to an aggressive type of breast cancer called estrogen receptor-negative cancer. In this preliminary study, estrogen-negative breast cancer developed when three markers, CD44+, CD49fhi, and CD133hi were present simultaneously on the surface of human cells taken from breast cancer patients and transplanted into a ... Read more...
12. Heart CT scans may help emergency room personnel more quickly assess patients with chest pain Adding computed tomography (CT) scans to standard screening procedures may help emergency room staff more rapidly determine which patients complaining of chest pain are having a heart attack or may soon have a heart attack, and which patients can be safely discharged, according to a study funded by the National Heart, Lung, and Blood Institute ... Read more...
13. Clinical trial stopped on combination cholesterol treatment The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial studying a blood lipid treatment 18 months earlier than planned. The trial found that adding high dose, extended-release niacin to statin treatment in people with heart and vascular disease, did not reduce the risk of cardiovascular ... Read more...
14. Finding of long sought drug target structure may expedite drug discovery Researchers have solved the three-dimensional structure of a key biological receptor. The finding has the potential to speed drug discovery in many areas, from arthritis to respiratory disorders to wound healing, because it enables chemists to better examine and design molecules for use in experimental drugs....
15. Study to test treatment for fatty liver disease in children With the launch of a new clinical trial supported by the National Institutes of Health, researchers are working to determine whether treating children diagnosed with the most severe form of fatty liver disease with a drug called cysteamine will help improve the liver....