National Institutes of Health researchers and grantees have found that gene variants in APOL1, more common in African Americans, come with both health risk and reward, as reported in the July 15 online issue of Science.

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  1. Medicare, Gene Pattern, May Identify Kidney Transplant Recipients, Who Don’t Need Life-long Anti-rejection Drugs Researchers have identified a distinct pattern of gene expression in the largest reported group of kidney transplant recipients who have not rejected the transplant kidneys even though they stopped taking anti-rejection drugs. This finding may help identify other transplant recipients who could safely reduce or end use of immunosuppressive therapy. In 2008, more than 80,000 […]...
  2. Medicare, Medicare Card, Receptor Variant Influences, Dopamine Response to Alcohol A genetic variant of a receptor in the brain’s reward circuitry plays an important role in determining whether the neurotransmitter dopamine is released in the brain following alcohol intake, according to a study led by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. Dopamine is […]...
  3. MedicareCard.com – Study Provides New Leads into Genetics of Cleft Lip and/or Palate A consortium of scientists supported by the National Institutes of Health reported today that it has identified two human genes that, when inherited in a slightly altered form, may play a role in causing cleft lip and/or palate (roof of the mouth), one of the world’s most common congenital malformations....
  4. Medicare Card: Gene Linked to Alzheimer’s Disease Plays Key Role in Cell Survival Scientists have discovered that a gene linked to Alzheimer’s disease may play a beneficial role in cell survival by enabling neurons to clear away toxic proteins. A study funded by the National Institute on Aging (NIA), part of the National Institutes of Health, shows the presenilin 1 (PS1) gene is essential to the function of […]...
  5. Medicare, Aiming for Near-Normal, Blood Sugar Did Not Delay Combined Risk of Diabetic Damage for People With Long-standing Diabetes, NIH-Sponsored Trial Finds In people with longstanding type 2 diabetes who are at high risk for heart attack and stroke, lowering blood sugar to near-normal levels did not delay the combined risk of diabetic damage to kidneys, eyes, or nerves, but did delay several other signs of diabetic damage, a study has found. The intensive glucose treatment was […]...
  6. Medicare Card News: NIH Researchers Explore How Healthy, Young Adults View the Role Genetics Plays in Improving Health Most healthy young adults place greater emphasis on health habits than on genetic risk factors when considering what causes common diseases, a research team from the National Human Genome Research Institute (NHGRI) and the Henry Ford Health System in Detroit has found. The study, based on a survey of 25- to-45-year-olds, was released June 8, […]...
  7. Medicare STAR METRICS, New Way to Measure the Impact of Federally Funded Research A new initiative promises to monitor the impact of federal science investments on employment, knowledge generation, and health outcomes. The initiative–Science and Technology for America’s Reinvestment: Measuring the Effect of Research on Innovation, Competitiveness and Science, or STAR METRICS–is a multi-agency venture led by the National Institutes of Health, the National Science Foundation (NSF), and […]...
  8. NIH-Supported ACCORD Eye Study Finds Two Therapies Slow Diabetic Eye Disease Progression In high-risk adults with type 2 diabetes, researchers have found that two therapies may slow the progression of diabetic retinopathy, an eye disease that is the leading cause of vision loss in working-age Americans....
  9. Medicare, NIH-Supported Study, Looks for Earliest Changes, in the Brain That May Lead to Alzheimer’s Disease Volunteers are being sought for a clinical study examining the subtle changes that may take place in the brains of older people many years before overt symptoms of Alzheimer’s disease appear. Researchers are looking for people with the very earliest complaints of memory problems that affect their daily activities. The study will follow participants over […]...
  10. NIH Genomic Mapping Study Finds Largest Set of Genes Related to Major Risk Factor for Heart Disease Scanning the genomes of more than 100,000 people from all over the world, scientists report the largest set of genes discovered underlying high cholesterol and high triglycerides — the major risk factors for coronary heart disease, the nation’s number one killer. Taken together, the gene variants explain between a quarter and a third of the […]...
  11. Medicare, Medicare Card, Study Finds Two Sling Surgeries, Equally Effective for Bladder Control in Women Two common operations for stress urinary incontinence (SUI) help women achieve similar levels of dryness, according to a team of urologists and urogynecologists who compared the treatments in a large U.S. trial supported by the National Institutes of Health. The study is being released online May 17, 2010, by the New England Journal of Medicine […]...
  12. Medicare Future? Pathways that Can Repair Brca1 Cancer Gene Mutation Clarified in Mice In a new study in mice, scientists have compensated for mutations in the Brca1 gene that can lead to cancer by deleting a second gene, which then lessens the probability of cancer. Mice Brca1-associated mammary tumors have significant similarities to human BRCA1- associated (BReast CAncer 1, early onset) breast cancer in regard to tumor aggressiveness, high incidence, mutations and genetic instability. The study, led by scientists at National Cancer Institute (NCI), part of the National Institutes of Health, and their colleagues, appeared online April 1, 2010 and in print April 16, 2010, in the journal Cell....
  13. Medicare, Medicare Card, NIH and Wellcome Trust Announce Partnership To Support Population-based Genome Studies in Africa The National Institutes of Health, an agency of the U.S. Department of Health and Human Services, and the Wellcome Trust, a global charity based in London, today announced a partnership to support population-based genetic studies in Africa of common, non-communicable disorders such as heart disease and cancer, as well as communicable diseases such as malaria. […]...
  14. MedicareCard.com, Experimental Immune, Boosting Drug Worsens TB in Mice An experimental drug that boosts production of the immune system protein interferon worsens tuberculosis (TB) in mice, according to scientists from the National Institutes of Health. The drug acts indirectly by drawing certain immune cells, in which Mycobacterium tuberculosis (M.tb) bacteria thrive, to the lungs. The findings may have potential implications for the care of people infected with TB, the authors note. The research is reported in the May 3 issue of Journal of Clinical Investigation, now available online....
  15. MedicareCard.com – Adding Coronary Calcium Score to Traditional Risk Factors Improves Risk Assessment for Heart Disease Including a coronary artery calcium score in a risk assessment for future heart disease events, such as heart attacks, provides a better estimate in some populations than a standard coronar...