Researchers show that anti-caries DNA vaccines, including pGJA-P/VAX, are good for preventing dental caries. In the report titled “Prospects in Caries Vaccine Development, it states that DNA vaccine approaches for dental caries have had a history of success in animal models. Dental caries vaccines, directed to key components of S. mutans colonization and enhanced by safe and effective adjuvants and optimal delivery vehicles, are likely to be forthcoming.