New programs exploring novel approaches to cell-to-cell communication and understanding undiagnosed diseases, which represent challenges or scientific opportunities for a wide array of health research, are the latest priorities for the National Institutes of Health Common Fund. The funding was announced today by NIH Director Francis S. Collins, M.D., Ph.D., after he received broad community input and recommendations from institute and center directors at NIH. The Common Fund targets strategic investments that have the potential for rapid and significant impact. The programs are scheduled to begin during fiscal year 2013.