Scientists have discovered that molecules called reactive oxygen species (ROS) produced by the energy factories, or mitochondria, in cells, may play a role in a rare inherited disorder in which uncontrolled inflammation damages the body’s tissues. Their research in human and mouse cells suggests that blocking these molecules could reduce inflammation in TNF receptor-associated periodic syndrome (TRAPS) and possibly other inflammatory diseases.

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  1. Medicare Card, Scientists Identify Markers, Human Breast Cancer Cells, Linked to Development of an Aggressive, But Less Common Form of Breast Cancer Scientists have identified a group of surface markers on cells linked to an aggressive type of breast cancer called estrogen receptor-negative cancer. In this preliminary study, estrogen-negative breast cancer developed when three markers, CD44+, CD49fhi, and CD133hi were present simultaneously on the surface of human cells taken from breast cancer patients and transplanted into a […]...
  2. Energy-Saving Tips During Energy Awareness Month, consider new ways of saving energy (and money) in your home....
  3. Researchers identify genetic cause of new vascular disease Clinical researchers at the National Institutes of Health’s Undiagnosed Diseases Program (UDP) have identified the genetic cause of a rare and debilitating vascular disorder not previously explained in the medical literature. The adult-onset condition is associated with progressive and painful arterial calcification affecting the lower extremities, yet spares patients’ coronary arteries. The new disease finding […]...
  4. Summit to focus on management of radiation dose in computerized tomography Members of the media are invited to attend a National Institutes of Health conference focused on transforming computed tomography (CT) technology and its use to achieve minimal public health risks from radiation exposure. A specific goal of this conference is to identify the technological steps and associated research required to reduce the radiation dose from […]...
  5. Celebrating Energy Statistics Our guest blogger today is Stacy MacIntyre, who works in the Office of Communication at the U.S. Energy Information Administration. Did you know … · Saudi Arabia was not the world’s top oil producer in 2009? · Renewable energy (biomass, hydropower, geothermal, solar, and wind) provides 8% of the total U.S. energy use? · Coal […]...
  6. Scientists find approach to enhance and prolong immune attack against tumor cells Investigators have identified a new class of human immune cells that behave like stem cells. These cells, a subtype of T lymphocytes, which comprise a small fraction of white blood cells, may prove more effective than any previously reported type of T cell for treating tumors. The study, by scientists at the National Cancer Institute […]...
  7. Uterine stem cells used to treat diabetes in mice Researchers funded by the National Institutes of Health have converted stem cells from the human endometrium into insulin-producing cells and transplanted them into mice to control the animals’ diabetes....
  8. Rare Disease Day at NIH presents latest research from various agencies and advocacy groups The National Institutes of Health will celebrate the Fourth Annual Rare Disease Day Feb. 28 with a day-long celebration co-sponsored by the NIH Office of Rare Diseases Research and the NIH Clinical Center. The event will recognize rare diseases research activities supported by several government agencies and advocacy organizations. Attendance is free and open to […]...
  9. MedicareCard.com – NIH Study Confirms Location of Stem Cells Near Cartilage-Rich Regions in Bones Working with mice, a team of researchers has pinpointed the location of bone generating stem cells in the spine, at the ends of shins, and in other bones. The team also has identified factors that control the stem cells’ growth. The research was conducted at the National Institutes of Health and other institutions....
  10. Researchers extend use of gene therapy to treat a soft tissue tumor Researchers extend use of gene therapy to treat a soft tissue tumor...
  11. Therapeutics for Rare and Neglected Diseases Program announces next round of drug development projects Researchers will begin drug development projects for rare and neglected diseases that include potential treatments for a musculoskeletal disorder, a cognitive dysfunction disorder, a virus that affects the central nervous system of newborns, a parasitic worm infection, a form of muscular dystrophy and a rare lung disease....
  12. Gene Mutations Linked to Early-Onset Inflammatory Bowel Disease An international team has discovered that mutations in either of 2 related genes cause a severe and rare form of inflammatory bowel disease in young children. The discovery allowed the researchers to successfully treat one of the study patients with a bone marrow transplant....
  13. How Medicare Coverage Can Help – Gene Mutations Linked to Early-Onset Inflammatory Bowel Disease An international team has discovered that mutations in either of 2 related genes cause a severe and rare form of inflammatory bowel disease in young children. The discovery allowed the researchers to successfully treat one of the study patients with a bone marrow transplant....
  14. NIH-Funded Researchers Generate Mature Egg Cells From Early Ovarian Follicles Researchers supported by the National Institutes of Health have for the first time activated mouse egg cells at the earliest stage of their development and brought them to maturity. In a related experiment, the researchers replicated the finding by also bringing human eggs to maturity in the laboratory....
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