Researchers will begin drug development projects for rare and neglected diseases that include potential treatments for a musculoskeletal disorder, a cognitive dysfunction disorder, a virus that affects the central nervous system of newborns, a parasitic worm infection, a form of muscular dystrophy and a rare lung disease.

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  1. Researchers create comprehensive collection of approved drugs to identify new therapies for rare and neglected diseases Researchers create comprehensive collection of approved drugs to identify new therapies for rare and neglected diseases...
  2. Blueprint empowers drug development for nervous system disorders The National Institutes of Health has made awards to investigators across the United States for an ambitious set of projects seeking to develop new drugs for disorders of the nervous system....
  3. Gene Associated with Rare Adrenal Disorder Appears To Trigger Cell Death, According to NIH Study A gene implicated in Carney complex, a rare disorder of the adrenal glands, appears to function as a molecular switch to limit cell growth and division, according to a study by researchers at the National Institutes of Health and other institutions....
  4. Rare Disease Day at NIH presents latest research from various agencies and advocacy groups The National Institutes of Health will celebrate the Fourth Annual Rare Disease Day Feb. 28 with a day-long celebration co-sponsored by the NIH Office of Rare Diseases Research and the NIH Clinical Center. The event will recognize rare diseases research activities supported by several government agencies and advocacy organizations. Attendance is free and open to […]...
  5. Medicare Help, Immune Cell’s Role, Lupus Nephritis Demonstrated, Paves Way for Safety Testing, of Potential New Use for Asthma Drug National Institutes of Health scientists have discovered that the activation of immune cells called basophils causes kidney damage in a mouse model of lupus nephritis. These findings and the team’s associated research in humans may lead to new treatments for this serious disease, a severe form of systemic lupus erythematosus (SLE) that affects the kidneys […]...
  6. Commonly used three-drug regimen for idiopathic pulmonary fibrosis found harmful The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has stopped one arm of a three arm multi-center, clinical trial studying treatments for the lung-scarring disease idiopathic pulmonary fibrosis (IPF) for safety concerns....
  7. Medicare Medical Care, Rapid Development of Drug-Resistant, 2009 H1N1 Influenza Reported in Two Cases Two people with compromised immune systems who became ill with 2009 H1N1 influenza developed drug-resistant strains of virus after less than two weeks on therapy, report doctors from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. Doctors who treat prolonged influenza infection should be aware that even a short course of antiviral treatment may lead to drug-resistant virus, say the authors, and clinicians should consider this possibility as they develop initial treatment strategies for their patients who have impaired immune function....
  8. Thirteen New Projects to Advance Asthma Control The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has approved the award of 13 contracts to local organizations across the country to develop, implement, and test science-based approaches to improve asthma control using evidence-based national guidelines for diagnosing and managing asthma....
  9. MedicareCard, Newer Heart Surgery, Infants Offers First-Year Survival Benefit over Traditional Procedure Infants born with a severely underdeveloped heart who undergo a newer surgical procedure are more likely to survive their first year and not require a heart transplant than those who have a more traditional surgical procedure, according to a report by researchers supported by the National Heart, Lung, and Blood Institute (NHLBI), which is part […]...
  10. Undiagnosed Diseases Program documents two-year pilot as clinic of last resort After its first two years of work, the Undiagnosed Diseases Program (UDP) of the National Institutes of Health is citing successes in patients whose cases have stumped specialists at leading medical institutions around the country....
  11. NIH Announces New Awards in Program to Expand Interdisciplinary Research Careers in Women’s Health Almost $6 million has been awarded to investigators and programs to help researchers in the early stages of careers in women’s health research. The funding is from the National Institutes of Health’s Office of Research on Women’s Health (ORWH) and other co-sponsors. The money will go to 12 new and continuing Building Interdisciplinary Research Careers […]...
  12. Scientists identify gene that could hold the key to muscle repair Researchers have long questioned why patients with Duchenne muscular dystrophy (DMD) tend to manage well through childhood and adolescence, yet succumb to their disease in early adulthood, or why elderly people who lose muscle strength following bed rest find it difficult or impossible to regain. Now, researchers at the National Institute of Arthritis and Musculoskeletal […]...
  13. Medicare, NIH announces new program to accelerate research independence The National Institutes of Health intends to invest approximately $60 million over the next five years in the NIH Director’s Early Independence Award (EIA) program to help junior investigators leapfrog over traditional post-doctoral training and move into independent academic positions at U.S. institutions, directly upon completion of their graduate research degrees....
  14. Statement of Anthony S. Fauci, M.D., and Jack Whitescarver, Ph.D., National Institutes of Health, on the 30th anniversary of the first reported cases of AIDS On June 5, 1981, an article concerning five previously healthy, young gay men in Los Angeles diagnosed with Pneumocystis carinii pneumonia, an infection that usually appears only in individuals with substantial immune system damage, appeared in the Morbidity and Mortality Weekly Report, a publication of the Centers for Disease Control and Prevention....
  15. Researchers slow immune attack on ovaries in mice In a study of mice, researchers have slowed an immune system attack on the ovaries. The mice developed a disorder resembling primary ovarian insufficiency (POI), a menopause-like condition that affects women under the age of 40, sometimes years or even decades before normal menopause. The study was conducted by scientists at the National Institutes of […]...